TargetMol

PROTAC MDM2 Degrader-1

Product Code:
 
TAR-T18631
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T18631-100mg100mgEnquire
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TAR-T18631-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
PROTAC MDM2 Degrader-1 is a chemical compound that utilizes PROTAC technology to degrade MDM2. This compound is comprised of a highly effective MDM2 inhibitor, a linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
CAS:
2249944-98-5
Molecular Weight:
1463.33
Purity:
0.98
SMILES:
C(=O)(N1[C@]([C@](N=C1C2=C(OC(C)C)C=C(OC)C=C2)(C3=CC=C(Cl)C=C3)[H])(C4=CC=C(Cl)C=C4)[H])N5CC(=O)N(CC(NCCCOCCOCCOCCCNC(CN6C(=O)CN(C(=O)N7[C@]([C@](N=C7C8=C(OC(C)C)C=C(OC)C=C8)(C9=CC=C(Cl)C=C9)[H])(C%10=CC=C(Cl)C=C%10)[H])CC6)=O)=O)CC5

References

Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A.