TargetMol

Thalidomide-O-amido-C8-NH2 hydrochloride

Product Code:
 
TAR-T18817
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T18817-100mg100mgEnquire
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TAR-T18817-500mg500mgEnquire
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Further Information

Bioactivity:
Thalidomide-O-amido-C8-NH2 hydrochloride is a synthetic conjugate of an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide and a linker. It can be utilized in the synthesis of PROTACs[1].
CAS:
T18817
Molecular Weight:
494.97
Purity:
0.98
SMILES:
O=C(NCCCCCCCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.Cl

References

James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.