TargetMol

Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride

Product Code:
 
TAR-T18820
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. It is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation [1].
CAS:
2245697-84-9
Molecular Weight:
542.97
Purity:
0.98
SMILES:
Cl.O=C(NCCOCCOCCOCCN)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

References

Methods to induce targeted protein degradation through bifunctional molecules. WO2017007612A1.