TargetMol

UAA crosslinker 1

Product Code:
 
TAR-T18864
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T18864-100mg100mgEnquire
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TAR-T18864-500mg500mgEnquire
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Further Information

Bioactivity:
UAA crosslinker 1 hydrochloride is an Amber codon-activating agent utilized for the incorporation of non-canonical amino acids (ncAAs) into proteins. This incorporation is achieved in vivo by leveraging the promiscuous activity of specific wildtype and engineered aminoacyl-tRNA synthetases[1].
CAS:
1167421-25-1
Molecular Weight:
259.26
Purity:
0.98
SMILES:
C(NCCCC[C@@H](C(O)=O)N)(OCCN=[N+]=[N-])=O

References

VanBrunt MP, et al. Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry. Bioconjug Chem. 2015 Nov 18;26(11):2249-60.