TargetMol

4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine

Product Code:
 
TAR-T19142
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).
CAS:
566169-98-0
Molecular Weight:
319.22
Pathway:
Neuroscience
Purity:
0.98
SMILES:
BrC=1C=CC=2N=C(SC2C1)C3=CC=C(C=C3)NC
Target:
Beta Amyloid

References

Mathis CA, et al. Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents. J Med Chem. 2003 Jun 19;46(13):2740-54. Klunk W, et al. Amyloid imaging as a surrogate marker for efficacy of anti-amyloid therapies.