TargetMol

Aspartylglutamate

Product Code:
 
TAR-T20364
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T20364-100mg100mgEnquire
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TAR-T20364-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Aspartylglutamate is a precursor molecule. When it upon acetylation to N-acetyl-aspartyl-glutamate (NAAG) is used as a metabotropic glutamate mGlu receptor agonist.
CAS:
08/06/6157
Molecular Weight:
262.21
Purity:
0.98
SMILES:
[C@H](NC([C@H](CC(O)=O)N)=O)(CCC(O)=O)C(O)=O

References

Cuchra M, Szaflik JP, Przybylowska-Sygut K, Gacek M, Kaminska A, Szaflik J, Majsterek I. The role of the 148 Asp/Glu polymorphism of the APE1 gene in the development and progression of primary open angle glaucoma development in the Polish population. Pol J Pathol. 2013 Dec;64(4):296-302. PubMed PMID: 24375045. Wang YY, Li YD, Liu JB, Ran XX, Guo YY, Ren NN, Chen X, Jiang H, Li YQ. Characterization and evolutionary implications of the triad Asp-Xxx-Glu in group II phosphopantetheinyl transferases. PLoS One. 2014 Jul 18;9(7):e103031. doi: 10.1371/journal.pone.0103031. eCollection 2014. PubMed PMID: 25036863; PubMed Central PMCID: PMC4103896. Baslow MH, Guilfoyle DN. Canavan disease, a rare early-onset human spongiform leukodystrophy: insights into its genesis and possible clinical interventions. Biochimie. 2013 Apr;95(4):946-56. doi: 10.1016/j.biochi.2012.10.023. Epub 2012 Nov 11. PubMed PMID: 23151389. Vavrusova M, Skibsted LH. Calcium binding to dipeptides of aspartate and glutamate in comparison with orthophosphoserine. J Agric Food Chem. 2013 Jun 5;61(22):5380-4. doi: 10.1021/jf400741e. Epub 2013 May 24. PubMed PMID: 23682986.