TargetMol

Fluorescein diphosphate

Product Code:
 
TAR-T20421
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Fluorescein diphosphate is a colorless and nonfluorescent substrate for alkaline phosphatases. The sequential alkaline phosphatase mediated hydrolysis of its two phosphate substituents yielding weakly fluorescent fluorescein monophosphate followed by strongly fluorescent fluorescein.
CAS:
217305-49-2
Molecular Weight:
509.3
Purity:
0.98
SMILES:
O=C1OC2(C3=CC=C(OP(=O)(O)O)C=C3OC4=CC(OP(=O)(O)O)=CC=C42)C=5C=CC=CC15.N

References

Yang X, Shen S, Guo L, Tan J, Lei H, Wu J, Zhao L, Xiong T, Wu Y, Cheng Y, Zhang Y. An Enzyme-Responsive "Turn-on" Fluorescence Polymeric Superamphiphile as a Potential Visualizable Phosphate Prodrug Delivery Vehicle. Macromol Biosci. 2018 Jun;18(6):e1800045. doi: 10.1002/mabi.201800045. Epub 2018 May 7. PubMed PMID: 29732741. Guha Mazumder A, Chatterjee S, Chatterjee S, Gonzalez JJ, Bag S, Ghosh S, Mukherjee A, Chatterjee J. Spectropathology-corroborated multimodal quantitative imaging biomarkers for neuroretinal degeneration in diabetic retinopathy. Clin Ophthalmol. 2017 Nov 22;11:2073-2089. doi: 10.2147/OPTH.S140110. eCollection 2017. PubMed PMID: 29200821; PubMed Central PMCID: PMC5703157. Zhou X, Zhou X, Zheng B. Stacking chip for quantitative bioanalysis. Talanta. 2017 Dec 1;175:483-487. doi: 10.1016/j.talanta.2017.07.077. Epub 2017 Jul 25. PubMed PMID: 28842021. Wang K, Chen Z, Huang L, Meng B, Zhou X, Wen X, Ren D. Naringenin reduces oxidative stress and improves mitochondrial dysfunction via activation of the Nrf2/ARE signaling pathway in neurons. Int J Mol Med. 2017 Nov;40(5):1582-1590. doi: 10.3892/ijmm.2017.3134. Epub 2017 Sep 13. PubMed PMID: 28949376.