TargetMol

Tyrosylleucine

Product Code:
 
TAR-T20443
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Tyrosylleucine is a dipeptide composed of tyrosine and leucine. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.
CAS:
17355-10-1
Molecular Weight:
294.35
Purity:
0.98
SMILES:
C([C@@H](C(N[C@@H](CC(C)C)C(O)=O)=O)N)C1=CC=C(O)C=C1

References

Moreira IP, Sasselli IR, Cannon DA, Hughes M, Lamprou DA, Tuttle T, Ulijn RV. Enzymatically activated emulsions stabilised by interfacial nanofibre networks. Soft Matter. 2016 Mar 7;12(9):2623-31. doi: 10.1039/c5sm02730f. Epub 2016 Feb 1. PubMed PMID: 26905042. Kanegawa N, Suzuki C, Ohinata K. Dipeptide Tyr-Leu (YL) exhibits anxiolytic-like activity after oral administration via activating serotonin 5-HT1A, dopamine D1 and GABAA receptors in mice. FEBS Lett. 2010 Feb 5;584(3):599-604. doi: 10.1016/j.febslet.2009.12.008. Epub 2009 Dec 23. PubMed PMID: 20005875. Mizushige T, Kanegawa N, Yamada A, Ota A, Kanamoto R, Ohinata K. Aromatic amino acid-leucine dipeptides exhibit anxiolytic-like activity in young mice. Neurosci Lett. 2013 May 24;543:126-9. doi: 10.1016/j.neulet.2013.03.043. Epub 2013 Apr 6. PubMed PMID: 23570730. Domingues P, Fonseca C, Reis A, Domingues MR. Identification of isomeric spin adducts of Leu-Tyr and Tyr-Leu free radicals using liquid chromatography-tandem mass spectrometry. Biomed Chromatogr. 2012 Jan;26(1):51-60. doi: 10.1002/bmc.1624. Epub 2011 Mar 23. PubMed PMID: 21432862.