TargetMol

JH-VIII-49

Product Code:
 
TAR-T24200
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T24200-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T24200-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
JH-VIII-49 is an effective and selective inhibitor of CDK8.
CAS:
T24200
Molecular Weight:
428.66
Purity:
0.98
SMILES:
C[C@@]12[C@@H](C3=CC4=C(C=C3)C=CN=C4)CC[C@@]1([H])[C@]5([H])CC=C6C[C@@H](N(C)C)CC[C@]6(C)C5CC2

References

Development of Highly Potent and Selective Steroidal Inhibitors and Degraders of CDK8 John M. Hatcher, Eric S. Wang, Liv Johannessen, Nicholas Kwiatkowski, Taebo Sim and Nathanael S. Gray Publication Date (Web): March 18, 2018 (Letter) doi: 10.1021/acsmedchemlett.8b00011