TargetMol

MK 0852

Product Code:
 
TAR-T24474
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T24474-100mg100mgEnquire
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TAR-T24474-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
MK 0852 is the platelet GP IIb/IIIa cyclic heptapeptide antagonist.
CAS:
138199-64-1
Molecular Weight:
869.98
Purity:
0.98
SMILES:
O=C1N2[C@](C(=O)N[C@@H](CC3=CC=C(CN)C=C3)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(O)=O)CSSC[C@H](NC(C)=O)C(=O)N[C@H]1CC(N)=O)(C(C)(C)SC2)[H]

References

Zhao L, Bath P, L?sche W, Heptinstall S. Platelet-monocyte interaction and GPIIb/IIIa blockade. Thromb Haemost. 2004 Oct;92(4):888-90. PubMed PMID: 15467921. Zhao L, Bath PM, Fox S, May J, Judge H, L?sche W, Heptinstall S. The effects of GPIIb-IIIa antagonists and a combination of three other antiplatelet agents on platelet-leukocyte interactions. Curr Med Res Opin. 2003;19(3):178-86. PubMed PMID: 12803731. Lages B, Weiss HJ. Greater inhibition of platelet procoagulant activity by antibody-derived glycoprotein IIb--IIIa inhibitors than by peptide and peptidomimetic inhibitors. Br J Haematol. 2001 Apr;113(1):65-71. PubMed PMID: 11328283. Zhao L, Bath PM, May J, L?sche W, Heptinstall S. P-selectin, tissue factor and CD40 ligand expression on platelet-leucocyte conjugates in the presence of a GPIIb/IIIa antagonist. Platelets. 2003 Nov-Dec;14(7-8):473-80. Erratum in: Platelets. 2004 Feb;15(1):63. PubMed PMID: 14713516.