TargetMol

Tolypomycin Y

Product Code:
 
TAR-T24895
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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This product comes from: United States.
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Further Information

Bioactivity:
Tolypomycin Y is a naturally occurring ansamycin antibiotic.
CAS:
23412-26-2
Molecular Weight:
822.905
Purity:
0.98
SMILES:
[H][C@]12C[C@@]1([H])C(=O)\C=C(C)/C(=O)NC1=CC(=N[C@@H]3CC[C@@H](O)O[C@H]3C)c3c4C(=O)[C@](C)(Oc4c(C)c(O)c3C1=O)O\C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@H]2O |w:15.26,c:46,t:8,14|

References

Bellomo P, Brufani M, Marchi E, Mascellani G, Melloni W, Montecchi L, Stanzani L. Synthesis and antibacterial activity of some derivatives of tolypomycinone. Relationship between structure and activity in ansamycins. J Med Chem. 1977 Oct;20(10):1287-91. PubMed PMID: 333113. Stanzani L, Venturini AP, Mantovani V. A new tolypomycin-Y derivative: in vitro and in vivo antimicrobial activity. J Antibiot (Tokyo). 1978 Nov;31(11):1195-200. PubMed PMID: 721713. Hasegawa T. Tolypomycin, a new antibiotic. VII. Assay method for tolypomycin Y. J Antibiot (Tokyo). 1972 Jan;25(1):25-9. PubMed PMID: 5010642. Marshall VP, Cialdella JI, Ohlmann GM, Gray GD. MIC values do not predict the intraphagocytic killing of Staphylococcus aureus by naphthalenic ansamycins. J Antibiot (Tokyo). 1983 Nov;36(11):1549-60. PubMed PMID: 6140253.