TargetMol

Aprofene

Product Code:
 
TAR-T25104
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T25104-100mg100mgEnquire
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TAR-T25104-500mg500mgEnquire
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Further Information

Bioactivity:
Aprofene (Aprophen) is an antagonist of muscarinic and nicotinic acetylcholine receptors. It may be used in the therapy of peptic ulcers, endarteritis (inflammation of the inner shell of the artery), cholecystitis (inflammation of the gallbladder), and spastic colitis.
CAS:
07/01/3563
Formula:
C21H27NO2
Molecular Weight:
325.44
Purity:
0.98
SMILES:
O=C(OCCN(CC)CC)C(C=1C=CC=CC1)(C=2C=CC=CC2)C

References

Gordon RK, Padilla FN, Moore E, Doctor BP, Chiang PK. Antimuscarinic activity of aprophen. Biochem Pharmacol. 1983 Oct 1;32(19):2979-81. PubMed PMID: 6626268. Arima N, Uchida Y, Yu R, Nakayama K, Nishina H. Acetylcholine receptors regulate gene expression that is essential for primitive streak formation in murine embryoid bodies. Biochem Biophys Res Commun. 2013 Jun 7;435(3):447-53. doi: 10.1016/j.bbrc.2013.05.006. Epub 2013 May 10. PubMed PMID: 23665324. Grudev D. [Delivery in prolonged pregnancy following preparation and induction with aprofen and prednisolone]. Akush Ginekol (Sofiia). 1990;29(3):14-8. Bulgarian. PubMed PMID: 2252139. Grudev D, Novachkov L, Geshev G, Krushkov I. [Use of aprophen in the preparation for and induction of labor]. Akush Ginekol (Sofiia). 1988;27(4):39-43. Bulgarian. PubMed PMID: 3218679.