TargetMol

Bradykinin potentiator-5

Product Code:
 
TAR-T25173
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-T25173-100mg100mgEnquire
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TAR-T25173-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall.
CAS:
30505-63-6
Molecular Weight:
611.7
Purity:
0.98
SMILES:
C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(O)=O

References

Shi D, Luo Y, Du Q, Wang L, Zhou M, Ma J, Li R, Chen T, Shaw C. A novel bradykinin-related dodecapeptide (RVALPPGFTPLR) from the skin secretion of the Fujian large-headed frog (Limnonectes fujianensis) exhibiting unusual structural and functional features. Toxins (Basel). 2014 Sep 29;6(10):2886-98. doi: 10.3390/toxins6102886. PubMed PMID: 25268979; PubMed Central PMCID: PMC4210874. Balaguer JM, Yu C, Byrne JG, Ball SK, Petracek MR, Brown NJ, Pretorius M. Contribution of endogenous bradykinin to fibrinolysis, inflammation, and blood product transfusion following cardiac surgery: a randomized clinical trial. Clin Pharmacol Ther. 2013 Apr;93(4):326-34. doi: 10.1038/clpt.2012.249. Epub 2012 Dec 24. PubMed PMID: 23361105; PubMed Central PMCID: PMC4031681. Jiang Y, Xi X, Ge L, Yang N, Hou X, Ma J, Ma C, Wu Y, Guo X, Li R, Zhou M, Wang L, Chen T, Shaw C. Bradykinin-related peptides (BRPs) from skin secretions of three genera of phyllomedusine leaf frogs and their comparative pharmacological effects on mammalian smooth muscles. Peptides. 2014 Feb;52:122-33. doi: 10.1016/j.peptides.2013.12.013. Epub 2014 Jan 3. PubMed PMID: 24394432. Uzawa A, Mori M, Taniguchi J, Kuwabara S. Modulation of the kallikrein/kinin system by the angiotensin-converting enzyme inhibitor alleviates experimental autoimmune encephalomyelitis. Clin Exp Immunol. 2014 Nov;178(2):245-52. doi: 10.1111/cei.12413. PubMed PMID: 24996009; PubMed Central PMCID: PMC4233374.