TargetMol

Budesonide mixture with salmeterol

Product Code:
 
TAR-T25182
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Budesonide mixture with salmeterol is used as a β2 -agonist.
CAS:
1535180-43-8
Molecular Weight:
846.1
Purity:
0.98
SMILES:
C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(CCC)O2)[H])([C@]4([C@]([C@@H](O)C3)([C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H])[H].C(CNCCCCCCOCCCCC1=CC=CC=C1)(O)C2=CC(CO)=C(O)C=C2

References

Cossette B, Beauchesne MF, Forget A, Lemi?re C, Lariv?e P, Rey E, Blais L. Relative perinatal safety of salmeterol vs formoterol and fluticasone vs budesonide use during pregnancy. Ann Allergy Asthma Immunol. 2014 May;112(5):459-64. doi: 10.1016/j.anai.2014.02.010. Epub 2014 Mar 19. PubMed PMID: 24656659. Larsson K, Janson C, Lisspers K, J?rgensen L, Stratelis G, Telg G, St?llberg B, Johansson G. Combination of budesonide/formoterol more effective than fluticasone/salmeterol in preventing exacerbations in chronic obstructive pulmonary disease: the PATHOS study. J Intern Med. 2013 Jun;273(6):584-94. doi: 10.1111/joim.12067. Epub 2013 Apr 1. PubMed PMID: 23495860. Tunceli O, Williams SA, Kern DM, Elhefni H, Pethick N, Wessman C, Zhou S, Trudo F. Comparative effectiveness of budesonide-formoterol combination and fluticasone-salmeterol combination for asthma management: a United States retrospective database analysis. J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):719-26. doi: 10.1016/j.jaip.2014.07.016. Epub 2014 Oct 3. PubMed PMID: 25439363. Akamatsu T, Shirai T, Kato M, Yasui H, Hashimoto D, Fujisawa T, Tsuchiya T, Inui N, Suda T, Chida K. Switching from salmeterol/fluticasone to formoterol/budesonide combinations improves peripheral airway/alveolar inflammation in asthma. Pulm Pharmacol Ther. 2014 Feb;27(1):52-6. doi: 10.1016/j.pupt.2013.04.001. Epub 2013 Apr 11. PubMed PMID: 23583566.