TargetMol

PYX 2

Product Code:
 
TAR-T26008
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-T26008-100mg100mgEnquire
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TAR-T26008-500mg500mgEnquire
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  • Further Information
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Further Information

Bioactivity:
PYX 2 is used as a neuropeptide Y receptor antagonist.
CAS:
146999-93-1
Molecular Weight:
1698.64
Purity:
0.98
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(Cc2c(Cl)cccc2Cl)c1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)c(Cc2c(Cl)cccc2Cl)c1)C(N)=O

References

Beck B, Stricker-Krongrad A, Musse N, Nicolas JP, Burlet C. Putative neuropeptide Y antagonist failed to decrease overeating in obese Zucker rats. Neurosci Lett. 1994 Nov 7;181(1-2):126-8. PubMed PMID: 7898751. Lee MC, Lawson DC, Pappas TN. Neuropeptide Y functions as a physiologic regulator of cephalic phase acid secretion. Regul Pept. 1994 Aug 4;52(3):227-34. PubMed PMID: 7800854. Leibowitz SF, Xuereb M, Kim T. Blockade of natural and neuropeptide Y-induced carbohydrate feeding by a receptor antagonist PYX-2. Neuroreport. 1992 Nov;3(11):1023-6. PubMed PMID: 1482761. Palea S, Corsi M, Rimland JM, Trist DG, Ratti E. Failure of the putative neuropeptide Y antagonists, benextramine and PYX-2, to inhibit Y2 receptors in rat isolated prostatic vas deferens. Br J Pharmacol. 1995 Nov;116(5):2401-6. PubMed PMID: 8581275; PubMed Central PMCID: PMC1909051.