TargetMol

Restricticin

Product Code:
 
TAR-T26064
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Restricticin is used as a naturally-occurring antifungal agent which contains triene, pyran and glycine ester functionalities.
CAS:
135357-96-9
Molecular Weight:
337.46
Purity:
0.98
SMILES:
CCC\C=C\C=C\C=C(/C)[C@@H]1OC[C@H](C)[C@H](OC)[C@H]1OC(=O)CN

References

Schwartz RE, Dufresne C, Flor JE, Kempf AJ, Wilson KE, Lam T, Onishi J, Milligan J, Fromtling RA, Abruzzo GK, et al. Restricticin, a novel glycine-containing antifungal agent. J Antibiot (Tokyo). 1991 May;44(5):463-71. PubMed PMID: 2061189. Tsukuda T, Shiratori Y, Watanabe M, Ontsuka H, Hattori K, Shirai M, Shimma N. Modeling, synthesis and biological activity of novel antifungal agents (1). Bioorg Med Chem Lett. 1998 Jul 21;8(14):1819-24. PubMed PMID: 9873440. Tsukuda T, Watanabe M, Ontsuka H, Hattori K, Shirai M, Shimma N. Synthesis of novel antifungal agents (2). Bioorg Med Chem Lett. 1998 Jul 21;8(14):1825-8. PubMed PMID: 9873441. VanMiddlesworth F, Milligan J, Bartizal K, Dufresne C, Onishi J, Abruzzo G, Patchett A, Wilson K. Carbazate as a glycine bioisostere in restricticin. J Antibiot (Tokyo). 1996 Mar;49(3):329-31. PubMed PMID: 8626254.