TargetMol

SW120

Product Code:
 
TAR-T26244
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T26244-100mg100mgEnquire
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TAR-T26244-500mg500mgEnquire
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Further Information

Bioactivity:
SW120 is used as a fluorescent sigma-2 selective ligand.
CAS:
1421931-14-7
Molecular Weight:
638.766
Purity:
0.98
SMILES:
COc1ccc(OC)c(NC(=O)OC2CC3CCCC(C2)N3CCCCCCCCCCNc2ccc(c3nonc23)N(=O)=O)c1 |TLB:12:13:21:16.17.18|

References

Bean DC, Wigmore SM, Wareham DW. Draft Genome Sequence of Staphylococcus cohnii subsp. urealyticus Isolated from a Healthy Dog. Genome Announc. 2017 Feb 16;5(7). pii: e01628-16. doi: 10.1128/genomeA.01628-16. PubMed PMID: 28209829; PubMed Central PMCID: PMC5313621. Xu J, Zeng C, Chu W, Pan F, Rothfuss JM, Zhang F, Tu Z, Zhou D, Zeng D, Vangveravong S, Johnston F, Spitzer D, Chang KC, Hotchkiss RS, Hawkins WG, Wheeler KT, Mach RH. Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site. Nat Commun. 2011 Jul 5;2:380. doi: 10.1038/ncomms1386. PubMed PMID: 21730960; PubMed Central PMCID: PMC3624020. Zeng C, Garg N, Mach RH. The PGRMC1 Protein Level Correlates with the Binding Activity of a Sigma-2 Fluorescent Probe (SW120) in Rat Brain Cells. Mol Imaging Biol. 2016 Apr;18(2):172-9. doi: 10.1007/s11307-015-0891-z. PubMed PMID: 26335282. Zeng C, Vangveravong S, Jones LA, Hyrc K, Chang KC, Xu J, Rothfuss JM, Goldberg MP, Hotchkiss RS, Mach RH. Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes. Mol Imaging. 2011 Dec;10(6):420-33. PubMed PMID: 22201533; PubMed Central PMCID: PMC4426860.