TargetMol

Allosamidin

Product Code:
 
TAR-T26595
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T26595-500mg500mgEnquire
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Further Information

Bioactivity:
Allosamidin, a chitinase inhibitor and typical secondary metabolite of Streptomyces, may be used as a pesticide and anti-asthmatic agent.
CAS:
103782-08-7
Molecular Weight:
622.625
Purity:
0.98
SMILES:
[H][C@@]12OC(=N[C@]1([H])[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]3NC(C)=O)[C@@H](O)[C@H]1NC(C)=O)[C@H]2CO)N(C)C |c:3|

References

Suzuki S, Nakanishi E, Ohira T, Kawachi R, Nagasawa H, Sakuda S. Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces I. Analysis of the chitinase whose production is promoted by allosamidin and growth accelerating activity of allosamidin. J Antibiot (Tokyo). 2006 Jul;59(7):402-9. PubMed PMID: 17025016. Wang Y, Liu T, Yang Q, Li Z, Qian X. A modeling study for structure features of ?-N-acetyl-D-hexosaminidase from Ostrinia furnacalis and its novel inhibitor allosamidin: species selectivity and multi-target characteristics. Chem Biol Drug Des. 2012 Apr;79(4):572-82. doi: 10.1111/j.1747-0285.2011.01301.x. Epub 2012 Jan 30. PubMed PMID: 22177554. Suzuki S, Nagasawa H, Sakuda S. Identification of the allosamidin-releasing factor in allosamidin-producing Streptomyces. J Antibiot (Tokyo). 2014 Feb;67(2):195-7. doi: 10.1038/ja.2013.109. Epub 2013 Oct 30. PubMed PMID: 24169800. Sato Y, Suzuki S, Muraoka S, Kikuchi N, Noda N, Matsumoto T, Inoue H, Nagasawa H, Sakuda S. Preparation of allosamidin and demethylallosamidin photoaffinity probes and analysis of allosamidin-binding proteins in asthmatic mice. Bioorg Med Chem. 2011 May 15;19(10):3054-9. doi: 10.1016/j.bmc.2011.04.012. Epub 2011 Apr 13. PubMed PMID: 21530272.