TargetMol

AWD12?281

Product Code:
 
TAR-T26694
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T26694-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26694-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
AWD12-281 is an inhibitor of PDE4.
CAS:
T26694
Molecular Weight:
443.26
Purity:
0.98
SMILES:
OC1=CC=C2C(C(C(C(C3=C(Cl)C=NC=C3Cl)=O)=O)=CN2CC4=CC=C(F)C=C4)=C1

References

Chan AL, Huang HL, Chien HC, Chen CM, Lin CN, Ko WC. Inhibitory effects of quercetin derivatives on phosphodiesterase isozymes and high-affinity [(3) H]-rolipram binding in guinea pig tissues. Invest New Drugs. 2008 Oct;26(5):417-24. doi: 10.1007/s10637-008-9114-7. Epub 2008 Feb 9. PubMed PMID: 18264679. Richter W, Unciuleac L, Hermsdorf T, Kronbach T, Dettmer D. Identification of inhibitor binding sites of the cAMP-specific phosphodiesterase 4. Cell Signal. 2001 Apr;13(4):287-97. PubMed PMID: 11306246.