TargetMol

CBIP

Product Code:
 
TAR-T26961
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T26961-100mg100mgEnquire
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TAR-T26961-500mg500mgEnquire
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Further Information

Bioactivity:
CBIP is a small-molecule inhibitors of botulinum neurotoxin serotype A light chain (BoNT/A LC). CBIP possesses low micromolar activity against BoNT/A.
CAS:
T26961
Molecular Weight:
328.8
Purity:
0.98
SMILES:
O=C(O)C1=NC=C(C(N2CCCC)=CC3=C2C=CC=C3Cl)C=C1

References

Bremer PT, Xue S, Janda KD. Picolinic acids as ?-exosite inhibitors of botulinum neurotoxin A light chain. Chem Commun (Camb). 2016 Oct 13;52(84):12521-12524. PubMed PMID: 27722252; PubMed Central PMCID: PMC5085802. Fresquet V, Williams L, Raushel FM. Partial randomization of the four sequential amidation reactions catalyzed by cobyric acid synthetase with a single point mutation. Biochemistry. 2007 Dec 11;46(49):13983-93. Epub 2007 Nov 15. PubMed PMID: 18001139; PubMed Central PMCID: PMC2518967. Wu YC, Leng CH, Hsieh WS, Hsu CH, Chen WJ, Gau SS, Chiu NC, Yang MC, Li-Jung Fang, Hsu HC, Yu YT, Wu YT, Chen LC, Jeng SF. A randomized controlled trial of clinic-based and home-based interventions in comparison with usual care for preterm infants: effects and mediators. Res Dev Disabil. 2014 Oct;35(10):2384-93. doi: 10.1016/j.ridd.2014.06.009. Epub 2014 Jun 26. PubMed PMID: 24973546. Wu YC, Hsieh WS, Hsu CH, Chang JH, Chou HC, Hsu HC, Chiu NC, Lee WT, Chen WJ, Ho YW, Jeng SF. Intervention effects on emotion regulation in preterm infants with very low birth weight: A randomize controlled trial. Res Dev Disabil. 2016 Jan;48:1-12. doi: 10.1016/j.ridd.2015.10.016. Epub 2015 Oct 31. PubMed PMID: 26524725.