TargetMol

PZ-285

Product Code:
 
TAR-T28478
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T28478-100mg100mgEnquire
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Further Information

Bioactivity:
PZ-285 is a potent anticancer agent with similar antitumor activity to the clinically active agent Dox. Pz 285 improves survival, inhibits primary tumor regrowth, and inhibits lung tumor metastasis compared to vehicle control animals.
CAS:
T28478
Molecular Weight:
890.9
Purity:
0.98
SMILES:
C[C@@]([C@](C)(OC)O1)(OC)OC(/C2=N/C3=N/C(C4=C3O[C@@](C)(OC)[C@](C)(OC)O4)=N\5)=C1/C(N2)=N/C(C6=C/7C(CCO)=CC=C6CCO)=NC7=N/C8=C(O[C@@](C)(OC)[C@](C)(OC)O9)C9=C5N8

References

Discovery of the Antitumor Effects of a Porphyrazine Diol (Pz 285) in MDA-MB-231 Breast Tumor Xenograft Models in Mice Irawati K. Kandela, Katherine J. McAuliffe, Lauren E. Cochran, Anthony G. M. Barrett, Brian M. Hoffman, Andrew P. Mazar, and Evan R. Trivedi Publication Date (Web): June 29, 2017 (Letter). DOI: 10.1021/acsmedchemlett.7b00063