TargetMol

RMPI-8226-38

Product Code:
 
TAR-T28546
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T28546-100mg100mgEnquire
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TAR-T28546-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
RMPI-8226-38 is an irreversible inhibitor of USP7 with IC50 value of 22 uM against RMPI-8226.
CAS:
T28546
Molecular Weight:
305.19
Purity:
0.98
SMILES:
CC(C1=CN=C(S1)SC2=C(Cl)C=NC=C2Cl)=O

References

Wu J, Kumar S, Wang F, Wang H, Chen L, Arsenault P, Mattern M, Weinstock J. Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7) Function for Oncology and Immune Oncology Therapies. J Med Chem. 2017 Aug 18. doi: 10.1021/acs.jmedchem.7b00498. [Epub ahead of print] PubMed PMID: 28768102.