TargetMol

SLC4101431

Product Code:
 
TAR-T28802
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T28802-100mg100mgEnquire
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TAR-T28802-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
SLC4101431 is a potent SphK2 inhibitor with Ki value of 90 nM.
CAS:
T28802
Molecular Weight:
558.1
Purity:
0.98
SMILES:
NC(N1CCC[C@H]1CC2=NC(C3=CC=C(NC4=NC(C5=CC=C(C6=CC=CC=C6)C=C5)=CS4)C=C3)=NO2)=[NH2+].[Cl-]

References

Childress ES, Kharel Y, Brown AM, Bevan DR, Lynch KR, Santos WL. Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and In Vivo Activity. J Med Chem. 2017 Apr 13. doi: 10.1021/acs.jmedchem.7b00233. [Epub ahead of print] PubMed PMID: 28406646.