TargetMol

SLUPP-225

Product Code:
 
TAR-T28807
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T28807-100mg100mgEnquire
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TAR-T28807-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
SLUPP-225 is an efflux pump inhibitor (EPI) by interacting with the membrane fusion protein AcrA, a critical component of the AcrAB-TolC efflux pump in Escherichia coli.
CAS:
T28807
Molecular Weight:
325.8
Purity:
0.98
SMILES:
O=C(NC1=CC=C(C2=NCCN2)C=C1)/C=C/C3=CC=CC=C3Cl

References

Haynes KM, Abdali N, Jhawar V, Zgurskaya HI, Parks JM, Green AT, Baudry JY, Rybenkov VV, Smith JC, Walker JK. Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. J Med Chem. 2017 Jun 26. doi: 10.1021/acs.jmedchem.7b00453. [Epub ahead of print] PubMed PMID: 28650638.