TargetMol

UK-414,495

Product Code:
 
TAR-T29052
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T29052-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T29052-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
UK-414,495 is a potent, selective inhibitor of the neutral endopeptidase, the enzyme normally serves to break down the neuropeptide VIP.
CAS:
337962-93-3
Molecular Weight:
339.45
Purity:
0.98
SMILES:
CCCC(CC1(CCCC1)C(=O)Nc1nnc(CC)s1)C(O)=O

References

Wayman CP, Baxter D, Turner L, Van Der Graaf PH, Naylor AM. UK-414,495, a selective inhibitor of neutral endopeptidase, potentiates pelvic nerve-stimulated increases in female genital blood flow in the anaesthetized rabbit. Br J Pharmacol. 2010 May;160(1):51-9. doi: 10.1111/j.1476-5381.2010.00691.x. PubMed PMID: 20412068; PubMed Central PMCID: PMC2860206.