TargetMol

YKL-04-085

Product Code:
 
TAR-T29176
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
YKL-04-085 is a potent inhibitor of viral translation. YKL-04-085 has cellular antiviral activity at 35-fold lower concentrations relative to inhibition of host-cell proliferation. YKL-04-085 demonstrated good inhibition of translation of the DENV2(GVD) reporter replicon in cellulo.
CAS:
2120356-29-6
Molecular Weight:
491.6
Purity:
0.98
SMILES:
O=C1N(C2=CC(NC(/C=C/CN(C)C)=O)=C(C=C2)C)C3=C(C=CC4=CC=C(C5=CN(C)N=C5)C=C43)C=C1

References

Structure?Activity Relationship Study of QL47: A Broad-Spectrum Antiviral Agent Yanke LiangMelissanne de WispelaereMargot CarocciQingsong LiuJinhua WangPriscilla L. YangNathanael S. Gray Publication Date (Web): February 3, 2017 (Letter) DOI: 10.1021/acsmedchemlett.7b00008