TargetMol

YM44781

Product Code:
 
TAR-T29185
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T29185-100mg100mgEnquire
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TAR-T29185-500mg500mgEnquire
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Further Information

Bioactivity:
YM44781 is a non-peptide tachykinin receptor antagonist. YM44781 exhibits high binding affinities at NK(1) (pK(i) = 9.09 +/- 0.02) and NK(2) (pK(i) = 9.94 +/- 0.03) receptors, respectively.
CAS:
173943-29-8
Molecular Weight:
568.51
Purity:
0.98
SMILES:
O=C(C1=CC=C(F)C=C1)N(C)CC(C2=CC=C(Cl)C(Cl)=C2)CCN3CCC4(NC(=O)CC=5C=CC=CC54)CC3

References

Choppin A, Groke G, Bringas A, Stepan G, Dillon MP. Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model. Pharmacology. 2002 May;65(2):96-102. PubMed PMID: 11937780.