TargetMol

(+)-Cloprostenol isopropyl ester, ethanol solution

Product Code:
 
TAR-T29246
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T29246-100mg100mgEnquire
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TAR-T29246-500mg500mgEnquire
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Further Information

Bioactivity:
(+)-Chloprostol is a PGF2α agonist and a similar synthetic prostaglandin F2α (PGF2α), which can induce luteal dissolution in mares during the luteal phase without causing clinical side effects or stress responses.
CAS:
157283-66-4
Molecular Weight:
466.99
Purity:
0.98
SMILES:
C(=C/[C@H](COC1=CC(Cl)=CC=C1)O)\[C@@H]2[C@@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](O)C[C@H]2O

References

Taktaz T, Kafi M, Mokhtari A, Heidari M. Reproductive responses of dairy cows with ovarian cysts to simultaneous human chorionic gonadotropin or gonadotropin-releasing hormone and cloprostenol compared to gonadotropin-releasing hormone alone treatment. Vet World. 2015 May;8(5):640-4. doi: 10.14202/vetworld.2015.640-644. Epub 2015 May 22. PubMed PMID: 27047149; PubMed Central PMCID: PMC4774727. Chen Y, Yan H, Chen HX, Weng J, Lu G. An Improved and Efficient Process for the Preparation of (+)-cloprostenol. Chirality. 2015 Jun;27(6):392-6. doi: 10.1002/chir.22457. Epub 2015 May 12. PubMed PMID: 25965955. Kuhl J, Nagel C, Ille N, Aurich JE, Aurich C. The PGF2? agonists luprostiol and d-cloprostenol reliably induce luteolysis in luteal phase mares without evoking clinical side effects or a stress response. Anim Reprod Sci. 2016 May;168:92-9. doi: 10.1016/j.anireprosci.2016.02.031. Epub 2016 Mar 2. PubMed PMID: 26963045. Wei S, Gong Z, An L, Zhang T, Dai H, Chen S. Cloprostenol and pregnant mare serum gonadotropin promote estrus synchronization, uterine development, and follicle-stimulating hormone receptor expression in mice. Genet Mol Res. 2015 Jun 29;14(2):7184-95. doi: 10.4238/2015.June.29.12. PubMed PMID: 26125929.