TargetMol

5-OH-PhIP

Product Code:
 
TAR-T29464
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
5-OH-PhIP is a PhIP metabolite.
CAS:
159471-46-2
Molecular Weight:
240.26
Purity:
0.98
SMILES:
O=C1NC=2N=C(N)N(C2C=C1C=3C=CC=CC3)C

References

Busquets R, Frandsen H, J?nsson J?, Puignou L, Galceran MT, Skog K. Biomonitoring of dietary heterocyclic amines and metabolites in urine by liquid phase microextraction: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a possible biomarker of exposure to dietary PhIP. Chem Res Toxicol. 2013 Feb 18;26(2):233-40. doi: 10.1021/tx3003966. Epub 2013 Jan 15. PubMed PMID: 23276304. Frandsen H. Deconjugation of N-glucuronide conjugated metabolites with hydrazine hydrate--biomarkers for exposure to the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Food Chem Toxicol. 2007 May;45(5):863-70. Epub 2006 Nov 16. PubMed PMID: 17184892. Frandsen H. Biomonitoring of urinary metabolites of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) following human consumption of cooked chicken. Food Chem Toxicol. 2008 Sep;46(9):3200-5. doi: 10.1016/j.fct.2008.07.008. Epub 2008 Jul 22. PubMed PMID: 18692111. Bellocq D, Molina J, Rathahao E, Canlet C, Tach? S, Martin PG, Pierre F, Paris A. High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation. Mutat Res. 2008 May 31;653(1-2):34-43. doi: 10.1016/j.mrgentox.2008.02.010. Epub 2008 Mar 15. PubMed PMID: 18434241.