TargetMol

7-Deoxyadriamycinol aglycone

Product Code:
 
TAR-T29483
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
7-Deoxyadriamycinol aglycone is an adriamycin metabolite.
CAS:
37818-13-6
Formula:
C21H20O8
Molecular Weight:
400.383
Purity:
0.98
SMILES:
COc1cccc2C(=O)c3c(O)c4C[C@](O)(CCc4c(O)c3C(=O)c12)[C@@H](O)CO

References

Dodion P, Riggs CE Jr, Akman SR, Bachur NR. Effect of hyperthermia on the in vitro metabolism of doxorubicin. Cancer Treat Rep. 1986 May;70(5):625-9. PubMed PMID: 3708610. Gille L, Nohl H. Analyses of the molecular mechanism of adriamycin-induced cardiotoxicity. Free Radic Biol Med. 1997;23(5):775-82. PubMed PMID: 9296455. Samuel L. Doxorubicin-induced cardiotoxicity. Postgrad Med J. 1995 May;71(835):318. PubMed PMID: 7596949; PubMed Central PMCID: PMC2398096. Cummings J, Milstead R, Cunningham D, Kaye S. Marked inter-patient variation in adriamycin biotransformation to 7-deoxyaglycones: evidence from metabolites identified in serum. Eur J Cancer Clin Oncol. 1986 Aug;22(8):991-1001. PubMed PMID: 3770056.