TargetMol

Aldoifosfamide

Product Code:
 
TAR-T29851
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T29851-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T29851-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Aldoifosfamide is a metabolite of ifosfamide. Ifosfamide (also marketed as Mitoxana and Ifex) is a nitrogen mustard alkylating agent used in the treatment of cancer. It is sometimes abbreviated 'IFO''.
CAS:
120144-70-9
Molecular Weight:
277.08
Purity:
0.98
SMILES:
O=CCCOP(=O)(NCCCl)NCCCl

References

Voelcker G. Influence of the alkylating function of aldoifosfamide on the antitumor activity. Anticancer Drugs. 2017 Oct 3. doi: 10.1097/CAD.0000000000000569. [Epub ahead of print] PubMed PMID: 28984684. Ludeman SM, Shulman-Roskes EM, Wong KK, Han SY, Anderson LW, Strong JM, Colvin OM. Oxime derivatives of the intermediary oncostatic metabolites of cyclophosphamide and ifosfamide: synthesis and deuterium labeling for applications to metabolite quantification. J Pharm Sci. 1995 Apr;84(4):393-8. PubMed PMID: 7629726. Masurel D, Houghton PJ, Young CL, Wainer IW. Efficacy, toxicity, pharmacokinetics, and in vitro metabolism of the enantiomers of ifosfamide in mice. Cancer Res. 1990 Jan 15;50(2):252-5. PubMed PMID: 2295063.