TargetMol

CRANAD-102

Product Code:
 
TAR-T31090
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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TAR-T31090-100mg100mgEnquire
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TAR-T31090-500mg500mgEnquire
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Further Information

Bioactivity:
CRANAD-102 is a probe for selectively detecting sAβ species in Alzheimer's disease (AD).
CAS:
T31090
Molecular Weight:
686.7
Purity:
0.98
SMILES:
FB1(F)O=C(/C=C/C2=CN=C(N(CCC)CCC)C=C2)C(CCCOC3=C(C)C=CC=C3C)=C(/C=C/C4=CN=C(N(CCC)CCC)C=C4)O1

References

Li Y, Yang J, Liu H, Yang J, Du L, Feng H, Tian Y, Cao J, Ran C. Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species. Chem Sci. 2017 Nov 1;8(11):7710-7717. doi: 10.1039/c7sc02050c. Epub 2017 Sep 15. PubMed PMID: 29568434; PubMed Central PMCID: PMC5851342. Yang J, Yang J, Li Y, Xu Y, Ran C. Near-infrared Fluorescence Ocular Imaging (NIRFOI) of Alzheimer's Disease. Mol Imaging Biol. 2018 May 25. doi: 10.1007/s11307-018-1213-z. [Epub ahead of print] PubMed PMID: 29802553.