TargetMol

D153249

Product Code:
 
TAR-T31168
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T31168-100mg100mgEnquire
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TAR-T31168-500mg500mgEnquire
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Further Information

Bioactivity:
D153249 is a promoter of spinal muscular atrophy (SMA).
CAS:
T31168
Molecular Weight:
314.77
Purity:
0.98
SMILES:
NC1=NC(N)=C2C(OC(C3=CC=CC(Cl)=C3)C)=CC=CC2=N1

References

Butchbach ME, Singh J, Thorsteinsd?ttir M, Saieva L, Slominski E, Thurmond J, Andr?sson T, Zhang J, Edwards JD, Simard LR, Pellizzoni L, Jarecki J, Burghes AH, Gurney ME. Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy. Hum Mol Genet. 2010 Feb 1;19(3):454-67. doi: 10.1093/hmg/ddp510. Epub 2009 Nov 6. PubMed PMID: 19897588; PubMed Central PMCID: PMC2798721.