TargetMol

Deacetyl-N,O-didemethyldiltiazem

Product Code:
 
TAR-T31247
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Deacetyl-N,O-didemethyldiltiazem is a biochemical.
CAS:
86408-42-6
Molecular Weight:
344.43
Purity:
0.98
SMILES:
C(CNC)N1C=2C(S[C@H]([C@@H](O)C1=O)C3=CC=C(O)C=C3)=CC=CC2

References

Zarev Y, Foubert K, Ionkova I, Apers S, Pieters L. Isolation and Structure Elucidation of Glucosylated Colchicinoids from the Seeds of Gloriosa superba by LC-DAD-SPE-NMR. J Nat Prod. 2017 Apr 28;80(4):1187-1191. doi: 10.1021/acs.jnatprod.6b01024. Epub 2017 Feb 17. PubMed PMID: 28211687. Ab O, Whiteman KR, Bartle LM, Sun X, Singh R, Tavares D, LaBelle A, Payne G, Lutz RJ, Pinkas J, Goldmacher VS, Chittenden T, Lambert JM. IMGN853, a Folate Receptor-? (FR?)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FR?-Expressing Tumors. Mol Cancer Ther. 2015 Jul;14(7):1605-13. doi: 10.1158/1535-7163.MCT-14-1095. Epub 2015 Apr 22. PubMed PMID: 25904506. Kumbhar BV, Borogaon A, Panda D, Kunwar A. Exploring the Origin of Differential Binding Affinities of Human Tubulin Isotypes ??II, ??III and ??IV for DAMA-Colchicine Using Homology Modelling, Molecular Docking and Molecular Dynamics Simulations. PLoS One. 2016 May 26;11(5):e0156048. doi: 10.1371/journal.pone.0156048. eCollection 2016. PubMed PMID: 27227832; PubMed Central PMCID: PMC4882049. Ho CT, Chang YJ, Yang LX, Wei PL, Liu TZ, Liu JJ. A Novel Microtubule-Disrupting Agent Induces Endoplasmic Reticular Stress-Mediated Cell Death in Human Hepatocellular Carcinoma Cells. PLoS One. 2015 Sep 10;10(9):e0136340. doi: 10.1371/journal.pone.0136340. eCollection 2015. PubMed PMID: 26355599; PubMed Central PMCID: PMC4565632.