TargetMol

Dexbrompheniramine maleate

Product Code:
 
TAR-T31396
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T31396-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Dexbrompheniramine is an antihistamine with anticholinergic properties. It is used to treat allergic diseases such as hay fever or urticaria. It can compete with histamine for H1 receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.
CAS:
09/03/2391
Molecular Weight:
435.318
Purity:
0.98
SMILES:
OC(=O)\C=C/C(O)=O.CN(C)CC[C@H](c1ccc(Br)cc1)c1ccccn1

References

Mar?k J, Mikus P, Mar?kov? K, Kaniansky D, Val?skov? I, Havr?nek E. Potentialities of ITP-CZE method with diode array detection for enantiomeric purity control of dexbrompheniramine in pharmaceuticals. J Pharm Biomed Anal. 2008 Apr 14;46(5):870-6. Epub 2007 May 25. PubMed PMID: 17618074. Onur F, Y?cesoy C, Dermi? S, Kartal M, K?kdil G. Simultaneous determination of pseudoephedrine sulfate, dexbrompheniramine maleate and loratadine in pharmaceutical preparations using derivative spectrophotometry and ratio spectra derivative spectrophotometry. Talanta. 2000 Feb 7;51(2):269-79. PubMed PMID: 18967858. Lin CC, Kim HK, Lim J, Digiore C, Symchowicz S, Gural R. Steady-state bioavailability of dexbrompheniramine and pseudoephedrine from a repeat-action combination tablet. J Pharm Sci. 1985 Jan;74(1):25-8. PubMed PMID: 3981411. Sadofsky LR, Campi B, Trevisani M, Compton SJ, Morice AH. Transient receptor potential vanilloid-1-mediated calcium responses are inhibited by the alkylamine antihistamines dexbrompheniramine and chlorpheniramine. Exp Lung Res. 2008 Dec;34(10):681-93. doi: 10.1080/01902140802339623. PubMed PMID: 19085565.