TargetMol

Enkephalin-met, acetaldehyde-

Product Code:
 
TAR-T31632
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Enkephalin-met, a naturally occurring opioid peptide used to regulate the growth of human colon cancer, can be used as an effective negative regulator of human gastrointestinal cancer and may suggest pathways for tumor etiology, progression, treatment and prevention.
CAS:
74080-62-9
Molecular Weight:
599.7
Purity:
0.98
SMILES:
CSCCC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CN1C(C)NC(Cc2ccc(O)cc2)C1=O)C(O)=O

References

Summers MC, Gidley MJ, Sanders JK. 'Acetaldehyde-enkephalins': elucidation of the structure of the acetaldehyde adducts of methionine-enkephalin and leucine-enkephalin. FEBS Lett. 1980 Mar 10;111(2):307-10. PubMed PMID: 7358173. Summers MC, Hayes RJ. Acetaldehyde-enkephalins: pronounced changes in the opiate activity of methionine-enkephalin and leucine-enkephalin on reaction with acetaldehyde. FEBS Lett. 1980 Apr 21;113(1):99-101. PubMed PMID: 6247206. Summers MC, Lightman SL. A reaction of acetaldehyde with enkephalins and related peptides. Biochem Pharmacol. 1981 Jun 15;30(12):1621-7. PubMed PMID: 6268105.