TargetMol

Fellutamide A

Product Code:
 
TAR-T31761
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T31761-500mg500mgEnquire
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Further Information

Bioactivity:
Fellutamide A as a tripeptide derivative from Penicillium fellutanum can enhance nerve growth factor (NGF) synthesis and secretion in vitro.
CAS:
138682-08-3
Molecular Weight:
571.716
Purity:
0.98
SMILES:
CCCCCCCCCC(O)CC(=O)NC(CC(N)=O)C(=O)NC(C(O)CC(N)=O)C(=O)NC(CC(C)C)C=O

References

Yamaguchi K, Tsuji T, Wakuri S, Yazawa K, Kondo K, Shigemori H, Kobayashi J. Stimulation of nerve growth factor synthesis and secretion by fellutamide A in vitro. Biosci Biotechnol Biochem. 1993 Feb;57(2):195-9. PubMed PMID: 7763492. Pirrung MC, Zhang F, Ambadi S, Gangadhara Rao Y. Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation. Org Biomol Chem. 2016 Sep 21;14(35):8367-75. doi: 10.1039/c6ob01233g. Epub 2016 Aug 17. PubMed PMID: 27533920; PubMed Central PMCID: PMC5303010. Schneekloth JS Jr, Sanders JL, Hines J, Crews CM. Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3855-8. Epub 2006 May 11. PubMed PMID: 16697191; PubMed Central PMCID: PMC2507734.