TargetMol

Iodoglibenclamide

Product Code:
 
TAR-T32173
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Iodoglibenclamide is a bioactive chemical.
CAS:
16789-77-8
Molecular Weight:
585.46
Purity:
0.98
SMILES:
O=C(NC1CCCCC1)NS(=O)(=O)C2=CC=C(C=C2)CCNC(=O)C3=CC(I)=CC=C3OC

References

Clement JP 4th, Kunjilwar K, Gonzalez G, Schwanstecher M, Panten U, Aguilar-Bryan L, Bryan J. Association and stoichiometry of K(ATP) channel subunits. Neuron. 1997 May;18(5):827-38. PubMed PMID: 9182806. Gehlert DR, Gackenheimer SL, Mais DE, Robertson DW. Quantitative autoradiography of the binding sites for [125I] iodoglyburide, a novel high-affinity ligand for ATP-sensitive potassium channels in rat brain. J Pharmacol Exp Ther. 1991 May;257(2):901-7. PubMed PMID: 1903447. Robertson DW, Schober DA, Krushinski JH, Mais DE, Thompson DC, Gehlert DR. Expedient synthesis and biochemical properties of an [125I]-labeled analogue of glyburide, a radioligand for ATP-inhibited potassium channels. J Med Chem. 1990 Dec;33(12):3124-6. PubMed PMID: 2124268. Gehlert DR, Mais DE, Gackenheimer SL, Krushinski JH, Robertson DW. Localization of ATP sensitive potassium channels in the rat brain using a novel radioligand, [125I]iodoglibenclamide. Eur J Pharmacol. 1990 Sep 21;186(2-3):373-5. PubMed PMID: 2127023.