TargetMol

IVDE77

Product Code:
 
TAR-T32240
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
IVDE77 is the first Ang IV-analogue with the ability to abolish IRAP-availability completely at the cell surface in vitro.
CAS:
T32240
Molecular Weight:
852.05
Purity:
0.98
SMILES:
NC[C@@H](C(C)C)C(N[C@H](C(N[C@@H]([C@H](CC)C)C(N[C@@H](CC1=C(NC2=C1C=CC=C2)C3)C(N3[C@@H](CCC)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)CC5=CC=C(O)C=C5)=O

References

Nikolaou A, Stijlemans B, Laoui D, Schouppe E, Tran HT, Tourw? D, Chai SY, Vanderheyden PM, Van Ginderachter JA. Presence and regulation of insulin-regulated aminopeptidase in mouse macrophages. J Renin Angiotensin Aldosterone Syst. 2014 Dec;15(4):466-79. doi: 10.1177/1470320313507621. Epub 2014 Feb 14. PubMed PMID: 24532823. Nikolaou A, Van den Eynde I, Tourw? D, Vauquelin G, T?th G, Mallareddy JR, Poglitsch M, Van Ginderachter JA, Vanderheyden PM. [3H]IVDE77, a novel radioligand with high affinity and selectivity for the insulin-regulated aminopeptidase. Eur J Pharmacol. 2013 Feb 28;702(1-3):93-102. doi: 10.1016/j.ejphar.2013.01.026. Epub 2013 Jan 31. PubMed PMID: 23376157.