TargetMol

Linagliptin mixture with metformin

Product Code:
 
TAR-T32758
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Linagliptin mixture with metformin is used for the treatment of type 2 diabetes.
CAS:
1198772-26-7
Molecular Weight:
601.71
Purity:
0.98
SMILES:
C(NC(=N)N)(N(C)C)=N.C(C#CC)N1C2=C(N=C1N3C[C@H](N)CCC3)N(C)C(=O)N(CC4=NC5=C(C(C)=N4)C=CC=C5)C2=O

References

El-Bagary RI, Elkady EF, Ayoub BM. Spectrophotometric Methods for the Determination of Linagliptin in Binary Mixture with Metformin Hydrochloride and Simultaneous Determination of Linagliptin and Metformin Hydrochloride using High Performance Liquid Chromatography. Int J Biomed Sci. 2013 Mar;9(1):41-7. PubMed PMID: 23675288; PubMed Central PMCID: PMC3644414. Vemula P, Dodda D, Balekari U, Panga S, Veeresham C. Simultaneous determination of linagliptin and metformin by reverse phase-high performance liquid chromatography method: An application in quantitative analysis of pharmaceutical dosage forms. J Adv Pharm Technol Res. 2015 Jan-Mar;6(1):25-8. doi: 10.4103/2231-4040.150368. PubMed PMID: 25709966; PubMed Central PMCID: PMC4330608. El-Kimary EI, Hamdy DA, Mourad SS, Barary MA. HPTLC Determination of Three Gliptins in Binary Mixtures with Metformin. J Chromatogr Sci. 2016 Jan;54(1):79-87. doi: 10.1093/chromsci/bmv106. Epub 2015 Jul 29. PubMed PMID: 26223462. Moussa BA, Mahrouse MA, Fawzy MG. Different resolution techniques for management of overlapped spectra: Application for the determination of novel co-formulated hypoglycemic drugs in their combined pharmaceutical dosage form. Spectrochim Acta A Mol Biomol Spectrosc. 2018 Jun 20;205:235-242. doi: 10.1016/j.saa.2018.06.072. [Epub ahead of print] PubMed PMID: 30025293.