TargetMol

Lipid Y

Product Code:
 
TAR-T32779
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-T32779-100mg100mgEnquire
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TAR-T32779-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
Lipid Y is a monosaccharide precursor of E coli lipid A.
CAS:
88090-57-7
Molecular Weight:
950.286
Purity:
0.98
SMILES:
CCCCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@H]1[C@@H](OP(O)(O)=O)O[C@H](CO)[C@@H](O)[C@@H]1OC(=O)C[C@H](O)CCCCCCCCCCC

References

Krishnan N, Malaga W, Constant P, Caws M, Tran TH, Salmons J, Nguyen TN, Nguyen DB, Daff? M, Young DB, Robertson BD, Guilhot C, Thwaites GE. Mycobacterium tuberculosis lineage influences innate immune response and virulence and is associated with distinct cell envelope lipid profiles. PLoS One. 2011;6(9):e23870. doi: 10.1371/journal.pone.0023870. Epub 2011 Sep 8. PubMed PMID: 21931620; PubMed Central PMCID: PMC3169546. Brozek KA, Bulawa CE, Raetz CR. Biosynthesis of lipid A precursors in Escherichia coli. A membrane-bound enzyme that transfers a palmitoyl residue from a glycerophospholipid to lipid X. J Biol Chem. 1987 Apr 15;262(11):5170-9. PubMed PMID: 3549717. Ikeda K, Nakamoto S, Takahashi T, Achiwa K. Lipid A and related compounds. XIV. A new synthesis of lipid Y, the reducing sugar moiety of Salmonella- and Proteus-type lipid A. Chem Pharm Bull (Tokyo). 1987 Nov;35(11):4436-41. PubMed PMID: 3442881. Nishijima M, Amano F, Akamatsu Y, Akagawa K, Tokunaga T, Raetz CR. Macrophage activation by monosaccharide precursors of Escherichia coli lipid A. Proc Natl Acad Sci U S A. 1985 Jan;82(2):282-6. PubMed PMID: 3881760; PubMed Central PMCID: PMC397021.