TargetMol

OPC 18692

Product Code:
 
TAR-T33805
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
OPC 18692 is a metabolite of Vesnarinone, a positive inotropic drug developed for congestive heart failure.
CAS:
211369-52-7
Formula:
C22H23N3O4
Molecular Weight:
393.44
Purity:
0.98
SMILES:
O=C(C1=CC=C(OC)C(OC)=C1)N2C=CN(C3=CC=C4NC(=O)CCC4=C3)CC2

References

Wandel C, Lang CC, Cowart DC, Girard AF, Bramer S, Flockhart DA, Wood AJ. Effect of CYP3A inhibition on vesnarinone metabolism in humans. Clin Pharmacol Ther. 1998 May;63(5):506-11. PubMed PMID: 9630823. Sekar KS, Bramer SL. Extended application of an LC-MS/MS method for the analysis of vesnarinone and its metabolites in human urine and dialysate fluid. J Pharm Biomed Anal. 2003 Nov 24;33(4):711-7. PubMed PMID: 14623597. Frye RF, Tammara B, Cowart TD, Bramer SL. Effect of disulfiram-mediated CYP2E1 inhibition on the disposition of vesnarinone. J Clin Pharmacol. 1999 Nov;39(11):1177-83. PubMed PMID: 10579149.