TargetMol

RPR-109891

Product Code:
 
TAR-T34405
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
RPR-109891 is a pseudo-tetrapeptide.
CAS:
169512-56-5
Molecular Weight:
523.675
Purity:
0.98
SMILES:
CCN(CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1CCCCC1)C(N)=O)C(=O)CCCC1CCNCC1

References

Giugliano RP, McCabe CH, Sequeira RF, Frey MJ, Henry TD, Piana RN, Tamby JF, Jensen BK, Nicolas SB, Jennings LK, Wise RJ, Braunwald E. First report of an intravenous and oral glycoprotein IIb/IIIa inhibitor (RPR 109891) in patients with recent acute coronary syndromes: results of the TIMI 15A and 15B trials. Am Heart J. 2000 Jul;140(1):81-93. PubMed PMID: 10874267. Weiss DJ, Mirsky ML, Evanson OA, Fagliari J, McClenahan D, McCullough B. Platelet kinetics in dogs treated with a glycoprotein IIb/IIIa peptide antagonist. Toxicol Pathol. 2000 Mar-Apr;28(2):310-6. PubMed PMID: 10805149. Catella-Lawson F, Kapoor S, Moretti D, De Marco S, Vigilante GJ, Cucchiara AJ, Ramsey KE, Combe S, Rocca B, Theroux P, FitzGerald GA; AFIRME Investigators. Antagonism of the Fibrinogen Receptor after Myocardial Events. Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease. Am J Cardiol. 2001 Aug 1;88(3):236-42. PubMed PMID: 11472700.