TargetMol

SK&F 107461

Product Code:
 
TAR-T34650
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T34650-100mg100mgEnquire
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TAR-T34650-500mg500mgEnquire
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Further Information

Bioactivity:
F 107461 is a hydroxyethylene dipeptide isostere.
CAS:
126380-03-8
Molecular Weight:
711.84
Purity:
0.98
SMILES:
[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC(OCC2=CC=CC=C2)=O)C)=O)C)=O)[C@H](CCC(N[C@H](C(N[C@H](C(OC)=O)C(C)C)=O)[C@@H](C)C)=O)O

References

Potts W, van Horn R, Anderson K, Blake T, Garver E, Joseph G, Dreyer G, Shu A, Heys R, Fong KL. Characterization of the metabolites of the peptidomimetic human immunodeficiency virus type 1 protease inhibitor SK&F 107461 in rats using liquid chromatography/mass spectrometry. Drug Metab Dispos. 1995 Aug;23(8):799-805. PubMed PMID: 7493545. Bugelski PJ, Kaplan JM, Hart TK, Miller J, Laydon JT, Lee JC, Dreyer GB, Kirsh R. Effect of a human immunodeficiency virus protease inhibitor on human monocyte function. AIDS Res Hum Retroviruses. 1992 Dec;8(12):1951-8. PubMed PMID: 1493045.