TargetMol

TCCP

Product Code:
 
TAR-T34791
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T34791-100mg100mgEnquire
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TAR-T34791-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
TCCP is a natural inducer of apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.
CAS:
T34791
Molecular Weight:
379.54
Purity:
0.98
SMILES:
O=C(C1=CNC=C1C(OCC(CCCC)CC)=O)OCC(CC)CCCC

References

Rashmi KC, Atreya HS, Harsha Raj M, Salimath BP, Aparna HS. A pyrrole-based natural small molecule mitigates HSP90 expression in MDA-MB-231 cells and inhibits tumor angiogenesis in mice by inactivating HSF-1. Cell Stress Chaperones. 2017 Sep;22(5):751-766. doi: 10.1007/s12192-017-0802-0. Epub 2017 Jul 17. PubMed PMID: 28717943; PubMed Central PMCID: PMC5573693. Rashmi KC, Harsha Raj M, Paul M, Girish KS, Salimath BP, Aparna HS. A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity. Chem Biol Interact. 2019 Feb 1;299:120-130. doi: 10.1016/j.cbi.2018.12.005. Epub 2018 Dec 10. PubMed PMID: 30543781.