TargetMol

5-Fluorouridine 5'-O-β-D-galactopyranoside

Product Code:
 
TAR-T38987
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
5-Fluorouridine 5'-O-β-D-galactopyranoside, also known as 5'-O-β-D-galactosyl-5-fluorouridine, is a prodrug of 5-Fluorouridine. 5-Fluorouridine 5'-O-β-D-galactopyranoside can be enzymatically converted by β-D-galactosidase into 5-Fluorouridine, which is a highly effective antineoplastic agent.
CAS:
149965-92-4
Molecular Weight:
424.334
Purity:
0.98
SMILES:
OC[C@H]1O[C@@H](OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cc(F)c(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@H]1O

References

R Abraham, et al. Conjugates of COL-1 monoclonal antibody and beta-D-galactosidase can specifically kill tumor cells by generation of 5-fluorouridine from the prodrug beta-D-galactosyl-5-fluorouridine. Cell Biophys. 1994;24-25:127-33.