TargetMol

Mal-amide-PEG2-oxyamine-Boc

Product Code:
 
TAR-T39791
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Mal-amide-PEG2-oxyamineBoc is a polyethylene glycol (PEG)-based linker molecule that possesses a Boc-protected oxyamine functionality. This compound serves as a valuable tool in the efficient synthesis of PROTACs (proteolysis targeting chimeras), offering a versatile and straightforward approach for constructing these targeted protein degradation agents.
CAS:
2253965-15-8
Molecular Weight:
415.443
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)NOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O |c:25|

References

An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.