TargetMol

HM Janelia Fluor® 526, SE

Product Code:
 
TAR-T39936
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
HM Janelia Fluor 526, SE (HM-JF526 NHS) is a derivative of hydroxymethyl JF526 (HM-JF526). SMLM (single-molecule localization microscopy) imaging in standard phosphate-buffered saline (pH 7.4) revealed that the HM-JF526 label showed spontaneous blinking behavior throughout the imaging session and did not require short-wavelength activation light. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
CAS:
2376841-30-2
Molecular Weight:
645.514
Purity:
0.98
SMILES:
Fc1cc2c(Oc3cc(N4CC(F)(F)C4)c(F)cc3C22OCc3ccc(cc23)C(=O)ON2C(=O)CCC2=O)cc1N1CC(F)(F)C1

References

Zheng Q, et al. Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging [published correction appears in ACS Cent Sci. 2020 Oct 28;6(10):1844]. ACS Cent Sci. 2019;5(9):1602-1613.