TargetMol

Tenofovir-C3-O-C15-CF3 ammonium

Product Code:
 
TAR-T40239
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T40239-500mg500mgEnquire
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Further Information

Bioactivity:
Tenofovir-C3-O-C15-CF3 (ammonium) demonstrates prolonged half-life values compared to tenofovir in human liver microsomes. It exhibits potent anti-HIV activity in vitro and enhances pharmacokinetic properties in vivo.
CAS:
2611373-80-7
Molecular Weight:
640.73
Purity:
0.98
SMILES:
N.C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OCCCOCCCCCCCCCCCCCCCC(F)(F)F

References

Pribut N, et al. ?-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties. J Med Chem. 2021 Sep 9;64(17):12917-12937.