TargetMol

Poly-D-lysine hydrobromide (MW 30000-70000)

Product Code:
 
TAR-T40363
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T40363-100mg100mgEnquire
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TAR-T40363-500mg500mgEnquire
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Further Information

Bioactivity:
Poly-D-lysine hydrobromide (MW 30,000-70,000) is a commonly employed synthetic polymeric substrate in neural cell culture, renowned for its efficacy. This compound efficiently eliminates proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells while concurrently leaving PrP C unaffected.
CAS:
27964-99-4
Molecular Weight:
227.102
Purity:
0.98
SMILES:
Br.NCCCC[C@@H](N)C(O)=O

References

HansVermeersch, et al. Immunogenicity of poly-D-lysine, a potential polymeric drug carrier. Journal of Controlled Release. Volume 32, Issue 3, 1 December 1994, Pages 225-229. Zhou Xu, et al. Mechanistic insights into cellular alteration of prion by poly-D-lysine: the role of H2H3 domain. FASEB J. 2011 Oct;25(10):3426-35.